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DDB1 and Cul4A Are Required for Human Immunodeficiency Virus Type 1 Vpr-Induced G(2) Arrest

Vpr-mediated induction of G(2) cell cycle arrest has been postulated to be important for human immunodeficiency virus type 1 (HIV-1) replication, but the precise role of Vpr in this cell cycle arrest is unclear. In the present study, we have shown that HIV-1 Vpr interacts with damaged DNA binding pr...

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Autors principals: Tan, Lindi, Ehrlich, Elana, Yu, Xiao-Fang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045451/
https://ncbi.nlm.nih.gov/pubmed/17626091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01380-07
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