Rift Valley Fever Virus Lacking the NSs and NSm Genes Is Highly Attenuated, Confers Protective Immunity from Virulent Virus Challenge, and Allows for Differential Identification of Infected and Vaccinated Animals

Rift Valley fever (RVF) virus is a mosquito-borne human and veterinary pathogen associated with large outbreaks of severe disease throughout Africa and more recently the Arabian peninsula. Infection of livestock can result in sweeping “abortion storms” and high mortality among young animals. Human i...

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Main Authors: Bird, Brian H., Albariño, César G., Hartman, Amy L., Erickson, Bobbie Rae, Ksiazek, Thomas G., Nichol, Stuart T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258974/
https://ncbi.nlm.nih.gov/pubmed/18199647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02501-07
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