Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

BACKGROUND: Previously, we investigated the role of the Rift Valley fever virus (RVFV) virulence genes NSs and NSm in mosquitoes and demonstrated that deletion of NSm significantly reduced the infection, dissemination, and transmission rates of RVFV in Aedes aegypti mosquitoes. The specific aim of t...

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Hlavní autoři: Kading, Rebekah C., Crabtree, Mary B., Bird, Brian H., Nichol, Stuart T., Erickson, Bobbie Rae, Horiuchi, Kalanthe, Biggerstaff, Brad J., Miller, Barry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923680/
https://ncbi.nlm.nih.gov/pubmed/24551252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002670
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