Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

BACKGROUND: Previously, we investigated the role of the Rift Valley fever virus (RVFV) virulence genes NSs and NSm in mosquitoes and demonstrated that deletion of NSm significantly reduced the infection, dissemination, and transmission rates of RVFV in Aedes aegypti mosquitoes. The specific aim of t...

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Detalhes bibliográficos
Main Authors: Kading, Rebekah C., Crabtree, Mary B., Bird, Brian H., Nichol, Stuart T., Erickson, Bobbie Rae, Horiuchi, Kalanthe, Biggerstaff, Brad J., Miller, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923680/
https://ncbi.nlm.nih.gov/pubmed/24551252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002670
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