Rift Valley Fever Virus Vaccine Lacking the NSs and NSm Genes Is Safe, Nonteratogenic, and Confers Protection from Viremia, Pyrexia, and Abortion following Challenge in Adult and Pregnant Sheep

Rift Valley fever virus (RVFV) is a mosquito-borne human and veterinary pathogen causing large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Safe and effective vaccines are critically needed, especially those that can be used in a targeted one-health approach to prevent bo...

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Detalhes bibliográficos
Main Authors: Bird, Brian H., Maartens, Louis H., Campbell, Shelley, Erasmus, Baltus J., Erickson, Bobbie R., Dodd, Kimberly A., Spiropoulou, Christina F., Cannon, Deborah, Drew, Clifton P., Knust, Barbara, McElroy, Anita K., Khristova, Marina L., Albariño, César G., Nichol, Stuart T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233145/
https://ncbi.nlm.nih.gov/pubmed/21976656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06046-11
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