Rift Valley Fever Virus Vaccine Lacking the NSs and NSm Genes Is Safe, Nonteratogenic, and Confers Protection from Viremia, Pyrexia, and Abortion following Challenge in Adult and Pregnant Sheep

Rift Valley fever virus (RVFV) is a mosquito-borne human and veterinary pathogen causing large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Safe and effective vaccines are critically needed, especially those that can be used in a targeted one-health approach to prevent bo...

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Bibliographic Details
Main Authors: Bird, Brian H., Maartens, Louis H., Campbell, Shelley, Erasmus, Baltus J., Erickson, Bobbie R., Dodd, Kimberly A., Spiropoulou, Christina F., Cannon, Deborah, Drew, Clifton P., Knust, Barbara, McElroy, Anita K., Khristova, Marina L., Albariño, César G., Nichol, Stuart T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233145/
https://ncbi.nlm.nih.gov/pubmed/21976656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06046-11
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