Relative Influence of the Adeno-Associated Virus (AAV) Type 2 p5 Element for Recombinant AAV Vector Site-Specific Integration

The p5 promoter region of the adeno-associated virus type 2 (AAV-2) rep gene has been described as essential for Rep-mediated site-specific integration (RMSSI) of plasmid sequences in human chromosome 19. We report here that insertion of a full-length or minimal p5 element between the viral inverted...

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Main Authors: Guilbaud, Mickaël, Chadeuf, Gilliane, Avolio, Fabio, François, Achille, Moullier, Philippe, Recchia, Alessandra, Salvetti, Anna
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Gene Delivery
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258927/
https://ncbi.nlm.nih.gov/pubmed/18094174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01956-07
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