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Dominant-Negative FADD Rescues the In Vivo Fitness of a Cytomegalovirus Lacking an Antiapoptotic Viral Gene

Genes that inhibit apoptosis have been described for many DNA viruses. Herpesviruses often contain even more than one gene to control cell death. Apoptosis inhibition by viral genes is postulated to contribute to viral fitness, although a formal proof is pending. To address this question, we studied...

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Bibliographische Detailangaben
Hauptverfasser: Čičin-Šain, Luka, Ruzsics, Zsolt, Podlech, Juergen, Bubić, Ivan, Menard, Carine, Jonjić, Stipan, Reddehase, Matthias J., Koszinowski, Ulrich H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258921/
https://ncbi.nlm.nih.gov/pubmed/18094168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01803-07
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