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Targeted Deletion of Regions Rich in Immune-Evasive Genes from the Cytomegalovirus Genome as a Novel Vaccine Strategy

Human cytomegalovirus (CMV), a ubiquitous human pathogen, is a leading cause of congenital infections and represents a serious health risk for the immunosuppressed patient. A vaccine against CMV is currently not available. CMV is characterized by its large genome and by multiple genes modulating the...

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Détails bibliographiques
Auteurs principaux: Čičin-Šain, Luka, Bubić, Ivan, Schnee, Margit, Ruzsics, Zsolt, Mohr, Christian, Jonjić, Stipan, Koszinowski, Ulrich H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168857/
https://ncbi.nlm.nih.gov/pubmed/17913824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-07
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