A Spread-Deficient Cytomegalovirus for Assessment of First-Target Cells in Vaccination

Human cytomegalovirus (HCMV) is a human pathogen that causes severe disease primarily in the immunocompromised or immunologically immature individual. To date, no vaccine is available. We describe use of a spread-deficient murine CMV (MCMV) as a novel approach for betaherpesvirus vaccination. To gen...

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Detalhes bibliográficos
Main Authors: Mohr, Christian Andreas, Arapovic, Jurica, Mühlbach, Hermine, Panzer, Marc, Weyn, Annelies, Dölken, Lars, Krmpotic, Astrid, Voehringer, David, Ruzsics, Zsolt, Koszinowski, Ulrich, Sacher, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897632/
https://ncbi.nlm.nih.gov/pubmed/20463067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02696-09
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