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Dominant-Negative FADD Rescues the In Vivo Fitness of a Cytomegalovirus Lacking an Antiapoptotic Viral Gene

Genes that inhibit apoptosis have been described for many DNA viruses. Herpesviruses often contain even more than one gene to control cell death. Apoptosis inhibition by viral genes is postulated to contribute to viral fitness, although a formal proof is pending. To address this question, we studied...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Čičin-Šain, Luka, Ruzsics, Zsolt, Podlech, Juergen, Bubić, Ivan, Menard, Carine, Jonjić, Stipan, Reddehase, Matthias J., Koszinowski, Ulrich H.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology (ASM) 2008
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258921/
https://ncbi.nlm.nih.gov/pubmed/18094168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01803-07
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