Isolation of a myoglobin molten globule by selective cobalt(III)-induced unfolding

Reaction of the Schiff-base complex [Co(acetylacetonate-ethylenediimine)(NH(3))(2)](+) with metmyoglobin at pH 6.5 yields a partially folded protein containing six Co(III) complexes. Although half of its α-helical secondary structure is retained, absorption and CD spectra indicate that the tertiary...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Blum, Ofer, Haiek, Abed, Cwikel, Dory, Dori, Zvi, Meade, Thomas J., Gray, Harry B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9618468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.12.6659
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