Isolation of a myoglobin molten globule by selective cobalt(III)-induced unfolding
Reaction of the Schiff-base complex [Co(acetylacetonate-ethylenediimine)(NH(3))(2)](+) with metmyoglobin at pH 6.5 yields a partially folded protein containing six Co(III) complexes. Although half of its α-helical secondary structure is retained, absorption and CD spectra indicate that the tertiary...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9618468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.12.6659 |
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