Suppressing Posttranslational Gluconoylation of Heterologous Proteins by Metabolic Engineering of Escherichia coli

Minimization of chemical modifications during the production of proteins for pharmaceutical and medical applications is of fundamental and practical importance. The gluconoylation of heterologously expressed protein which is observed in Escherichia coli BL21(DE3) constitutes one such undesired postt...

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Detalhes bibliográficos
Main Authors: Aon, Juan C., Caimi, Richard J., Taylor, Alexander H., Lu, Quinn, Oluboyede, Femi, Dally, Jennifer, Kessler, Michelle D., Kerrigan, John J., Lewis, Tia S., Wysocki, Lisa A., Patel, Pramatesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258596/
https://ncbi.nlm.nih.gov/pubmed/18083862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01790-07
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