Urine Bactericidal Activity against Escherichia coli Isolates Exhibiting Different Resistance Phenotypes/Genotypes in an In Vitro Pharmacodynamic Model Simulating Urine Concentrations Obtained after Oral Administration of a 400-Milligram Single Dose of Cefditoren-Pivoxil

Activity of simulated cefditoren urinary concentrations was determined against seven Escherichia coli isolates. Bactericidal activity was obtained from 4 to 24 h against TEM-1 (penicillinase production/hyperproduction), TEM-34 (IRT-6), and TEM-116 (extended-spectrum beta-lactamase [ESBL]) and from 6...

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Dettagli Bibliografici
Autori principali: Sevillano, David, Aguilar, Lorenzo, Alou, Luis, Giménez, María-José, Torrico, Martha, González, Natalia, Cafini, Fabio, Relaño, María-Teresa, Coronel, Pilar, Prieto, José
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258530/
https://ncbi.nlm.nih.gov/pubmed/18160517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01247-07
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