Influence of TEM-1 β-Lactamase on the Pharmacodynamic Activity of Simulated Total versus Free-Drug Serum Concentrations of Cefditoren (400 Milligrams) versus Amoxicillin-Clavulanic Acid (2,000/125 Milligrams) against Haemophilus influenzae Strains Exhibiting an N526K Mutation in the ftsI Gene

The aim of this study was to explore bactericidal activity of total and free serum simulated concentrations after the oral administration of cefditoren (400 mg, twice daily [bid]) versus the oral administration of amoxicillin-clavulanic acid extended release formulation (2,000/125 mg bid) against Ha...

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Autors principals: Torrico, M., Aguilar, L., González, N., Giménez, M. J., Echeverría, O., Cafini, F., Sevillano, D., Alou, L., Coronel, P., Prieto, J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043252/
https://ncbi.nlm.nih.gov/pubmed/17664320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-06
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