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Crystal Structure of a Thermally Stable Rhodopsin Mutant
We determined the structure of the rhodopsin mutant N2C/D282C expressed in mammalian cells; the first structure of a recombinantly produced G protein-coupled receptor (GPCR). The mutant was designed to form a disulfide bond between the N-terminus and loop E3 which allows handling of opsin in deterge...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258155/ https://ncbi.nlm.nih.gov/pubmed/17825322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.007 |
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