Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of RNase T1
An antibody generated to an α-keto amide containing hapten 1 catalyzes the cis-trans isomerization of peptidyl-prolyl amide bonds in peptides and in the protein RNase T1. The antibody-catalyzed peptide isomerization reaction showed saturation kinetics for the cis-substrate, Suc-Ala-Ala-Pro-Phe-pNA,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22581/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7251 |
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