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Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart
OBJECTIVE: Insulin regulates both glucose uptake and postnatal cardiac growth. The anabolic effects of insulin are mediated by the mammalian target of rapamycin (mTOR), an evolutionarily conserved kinase which is also a convergence point between nutrient sensing and cell growth. We postulated that m...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2257479/ https://ncbi.nlm.nih.gov/pubmed/17553476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2007.05.004 |
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