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The influence of esters and carboxylic acids as the N-substituent of opioids. 1. Benzomorphans
To investigate the effects of carboxylic ester and acid moieties as the N-substituent of opioids, a short series of racemic N-substituted normetazocines was prepared. The introduction of both groups as the normetazocine N-substituent produced compounds which displayed low potency in vitro and in viv...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254757/ https://ncbi.nlm.nih.gov/pubmed/17962026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.10.030 |
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