Modulation of DNA damage/DNA repair capacity by XPC polymorphisms

XPC, a key protein in the nucleotide excision repair (NER) pathway, recognizes damaged DNA and initiates NER. Genetic variations in the XPC gene might be associated with altered DNA repair capacities (DRC). In this study, we genotyped three XPC polymorphisms, Ala499Val (C→T), PAT (-/+) and Lys939Gln...

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Detalhes bibliográficos
Main Authors: Zhu, Yimin, Yang, Hushan, Chen, Qin, Lin, Jie, Grossman, H. Barton, Dinney, Colin P., Wu, Xifeng, Gu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254649/
https://ncbi.nlm.nih.gov/pubmed/17923445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.08.006
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