Microarray analysis of the in vivo sequence preferences of a minor groove binding drug

BACKGROUND: Minor groove binding drugs (MGBDs) interact with DNA in a sequence-specific manner and can cause changes in gene expression at the level of transcription. They serve as valuable models for protein interactions with DNA and form an important class of antitumor, antiviral, antitrypanosomal...

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Autors principals: Eckdahl, Todd T, Brown, Adam D, Hart, Steven N, Malloy, Kelly J, Shott, Martha, Yiu, Gloria, Hoopes, Laura L Mays, Heyer, Laurie J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254601/
https://ncbi.nlm.nih.gov/pubmed/18215295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-32
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