Microarray analysis of the in vivo sequence preferences of a minor groove binding drug

BACKGROUND: Minor groove binding drugs (MGBDs) interact with DNA in a sequence-specific manner and can cause changes in gene expression at the level of transcription. They serve as valuable models for protein interactions with DNA and form an important class of antitumor, antiviral, antitrypanosomal...

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Hauptverfasser: Eckdahl, Todd T, Brown, Adam D, Hart, Steven N, Malloy, Kelly J, Shott, Martha, Yiu, Gloria, Hoopes, Laura L Mays, Heyer, Laurie J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254601/
https://ncbi.nlm.nih.gov/pubmed/18215295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-32
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