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Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis
Combinatorial shotgun scanning mutagenesis was used to analyze two large, related protein binding sites to assess the specificity and importance of individual side chain contributions to binding affinity. The strategy allowed for cost-effective generation of a plethora of functional data. The ease o...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253482/ https://ncbi.nlm.nih.gov/pubmed/16131663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051519805 |
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