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Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor

We previously reported the construction of a family of reagentless fluorescent biosensor proteins by the structure-based design of conjugation sites for a single, environmentally sensitive small molecule dye, thus providing a mechanism for the transduction of ligand-induced conformational changes in...

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Detalhes bibliográficos
Main Authors: Dattelbaum, Jonathan D., Looger, Loren L., Benson, David E., Sali, Kevin M., Thompson, Richard B., Hellinga, Homme W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253422/
https://ncbi.nlm.nih.gov/pubmed/15659363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041146005
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