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The crystal structure of PfFabZ, the unique β-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum

The unique β-hydroxyacyl-ACP dehydratase in Plasmodium falciparum, PfFabZ, is involved in fatty acid biosynthesis and catalyzes the dehydration of β-hydroxy fatty acids linked to acyl carrier protein. The structure was solved by single anomalous dispersion (SAD) phasing using a quick-soaking experim...

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Detalhes bibliográficos
Main Authors: Kostrewa, Dirk, Winkler, Fritz K., Folkers, Gerd, Scapozza, Leonardo, Perozzo, Remo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253385/
https://ncbi.nlm.nih.gov/pubmed/15930004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051373005
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