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Charge–charge interactions in the denatured state influence the folding kinetics of ribonuclease Sa

Gaining a better understanding of the denatured state ensemble of proteins is important for understanding protein stability and the mechanism of protein folding. We studied the folding kinetics of ribonuclease Sa (RNase Sa) and a charge-reversal variant (D17R). The refolding kinetics are similar, bu...

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Detalles Bibliográficos
Autores principales: Trefethen, Jared M., Pace, C. Nick, Scholtz, J. Martin, Brems, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253365/
https://ncbi.nlm.nih.gov/pubmed/15937282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051401905
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