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Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities
Mammalian telomeres consist of long tandem arrays of double-stranded telomeric TTAGGG repeats packaged by the telomeric DNA-binding proteins TRF1 and TRF2. Both contain a similar C-terminal Myb domain that mediates sequence-specific binding to telomeric DNA. In a DNA complex of TRF1, only the single...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253311/ https://ncbi.nlm.nih.gov/pubmed/15608118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04983705 |
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