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Parallel interrogation of covalent intermediates in the biosynthesis of gramicidin S using high-resolution mass spectrometry
For determination of multiple covalent intermediates bound to the ultra-large enzymes responsible for biosynthesis via nonribosomal peptide synthesis, mass spectrometry (MS) is a promising method to provide new mechanistic insight. Application of a quadrupole-Fourier-transform instrument (Q-FTMS) fo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253301/ https://ncbi.nlm.nih.gov/pubmed/16195555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051553705 |
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