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Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia

The TEL (ETV6)−AML1 (CBFA2) gene fusion is the most common reciprocal chromosomal rearrangement in childhood cancer occurring in ≈25% of the most predominant subtype of leukemia— common acute lymphoblastic leukemia. The TEL-AML1 genomic sequence has been characterized in a pair of monozygotic twins...

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Main Authors: Ford, Anthony M., Bennett, Caroline A., Price, Cathy M., Bruin, M. C. A., Van Wering, Elisabeth R., Greaves, Mel
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC22533/
https://ncbi.nlm.nih.gov/pubmed/9539781
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