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The leukocidin pore: Evidence for an octamer with four LukF subunits and four LukS subunits alternating around a central axis

The staphylococcal α-hemolysin (αHL) and leukocidin (Luk) polypeptides are members of a family of related β-barrel pore-forming toxins. Upon binding to susceptible cells, αHL forms water-filled homoheptameric transmembrane pores. By contrast, Luk pores are formed by two classes of subunit, F and S,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jayasinghe, Lakmal, Bayley, Hagan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253299/
https://ncbi.nlm.nih.gov/pubmed/16195546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051648505
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