Crystal structure of the N-terminal domain of E. coli Lon protease

We report here the first crystal structure of the N-terminal domain of an A-type Lon protease. Lon proteases are ubiquitous, multidomain, ATP-dependent enzymes with both highly specific and non-specific protein binding, unfolding, and degrading activities. We expressed and purified a stable, monomer...

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Bibliographic Details
Main Authors: Li, Mi, Rasulova, Fatima, Melnikov, Edward E., Rotanova, Tatyana V., Gustchina, Alla, Maurizi, Michael R., Wlodawer, Alexander
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2005
Subjects:
Protein Structure Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253230/
https://ncbi.nlm.nih.gov/pubmed/16199667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051736805
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