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Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype

The new antigen receptor (IgNAR) antibodies from sharks are disulphide bonded dimers of two protein chains, each containing one variable and five constant domains. Three types of IgNAR variable domains have been discovered, with Type 3 appearing early in shark development and being overtaken by the...

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Autores principales: Streltsov, Victor A., Carmichael, Jennifer A., Nuttall, Stewart D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253229/
https://ncbi.nlm.nih.gov/pubmed/16199666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051709505
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