T cell positive selection by a high density, low affinity ligand
Interaction of the αβ T cell receptor (TCR) with major histocompatibility (MHC) molecules occupied with any of a large collection of peptides derived from self proteins is a critical step in driving T cell “positive” selection in the thymus. Interaction with this same pool of self-peptide/MHC ligand...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4522 |
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