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T cell positive selection by a high density, low affinity ligand

Interaction of the αβ T cell receptor (TCR) with major histocompatibility (MHC) molecules occupied with any of a large collection of peptides derived from self proteins is a critical step in driving T cell “positive” selection in the thymus. Interaction with this same pool of self-peptide/MHC ligand...

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Bibliografski detalji
Glavni autori: Liu, Chih-Pin, Crawford, Frances, Marrack, Philippa, Kappler, John
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC22522/
https://ncbi.nlm.nih.gov/pubmed/9539770
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