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Selection of Antigen-specific T Cells by a Single IE(k) Peptide Combination

In normal mice, major histocompatibility complex (MHC) proteins are bound to many different peptides, derived from the proteins of their host. In the thymus, the diversity of this collection of MHC + peptide ligands allows thymocytes bearing many different T cell receptors (TCRs) to mature by low av...

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Detalhes bibliográficos
Main Authors: Liu, Chih-Pin, Parker, David, Kappler, John, Marrack, Philippa
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199109/
https://ncbi.nlm.nih.gov/pubmed/9348301
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