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Selection of Antigen-specific T Cells by a Single IE(k) Peptide Combination

In normal mice, major histocompatibility complex (MHC) proteins are bound to many different peptides, derived from the proteins of their host. In the thymus, the diversity of this collection of MHC + peptide ligands allows thymocytes bearing many different T cell receptors (TCRs) to mature by low av...

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Autores principales: Liu, Chih-Pin, Parker, David, Kappler, John, Marrack, Philippa
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199109/
https://ncbi.nlm.nih.gov/pubmed/9348301
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