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General Strategy for Broadening Adenovirus Tropism
In spite of its broad host range, adenovirus type 5 (Ad5) transduces a number of clinically relevant tissues and cell types inefficiently, mostly because of low expression of the coxsackievirus-adenovirus receptor (CAR). To improve gene transfer to such cells, we modified the Ad5 fiber knob to recog...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC225005/ https://ncbi.nlm.nih.gov/pubmed/14512557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11094-11104.2003 |
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