Exploiting the Natural Diversity in Adenovirus Tropism for Therapy and Prevention of Disease

Since targeting of recombinant adenovirus vectors to defined cell types in vivo is a major challenge in gene therapy and vaccinology, we explored the natural diversity in human adenovirus tissue tropism. Hereto, we constructed a library of Ad5 vectors carrying fibers from other human serotypes. From...

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書誌詳細
主要な著者: Havenga, M. J. E., Lemckert, A. A. C., Ophorst, O. J. A. E., van Meijer, M., Germeraad, W. T. V., Grimbergen, J., van den Doel, M. A., Vogels, R., van Deutekom, J., Janson, A. A. M., de Bruijn, J. D., Uytdehaag, F., Quax, P. H. A., Logtenberg, T., Mehtali, M., Bout, A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
Gene Therapy
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC155076/
https://ncbi.nlm.nih.gov/pubmed/11932426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4612-4620.2002
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