Exploiting the Natural Diversity in Adenovirus Tropism for Therapy and Prevention of Disease

Since targeting of recombinant adenovirus vectors to defined cell types in vivo is a major challenge in gene therapy and vaccinology, we explored the natural diversity in human adenovirus tissue tropism. Hereto, we constructed a library of Ad5 vectors carrying fibers from other human serotypes. From...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Havenga, M. J. E., Lemckert, A. A. C., Ophorst, O. J. A. E., van Meijer, M., Germeraad, W. T. V., Grimbergen, J., van den Doel, M. A., Vogels, R., van Deutekom, J., Janson, A. A. M., de Bruijn, J. D., Uytdehaag, F., Quax, P. H. A., Logtenberg, T., Mehtali, M., Bout, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC155076/
https://ncbi.nlm.nih.gov/pubmed/11932426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4612-4620.2002
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi