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Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes

Nuclease type colicins and related bacteriocins possess the unprecedented ability to translocate an enzymatic polypeptide chain across the Gram-negative cell envelope. Here we use the rRNase domain of the cytotoxic ribonuclease colicin E3 to examine the structural changes on its interaction with the...

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Bibliografiske detaljer
Main Authors: Mosbahi, Khédidja, Walker, Daniel, James, Richard, Moore, Geoffrey R., Kleanthous, Colin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249781/
https://ncbi.nlm.nih.gov/pubmed/16452623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051890306
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