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Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3
Colicin E3 is a cytotoxic ribonuclease that specifically cleaves 16S rRNA at the ribosomal A-site to abolish protein synthesis in sensitive Escherichia coli cells. We have performed extensive mutagenesis of the 96-residue colicin E3 cytotoxic domain (E3 rRNase), assayed mutant colicins for in vivo c...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279995/ https://ncbi.nlm.nih.gov/pubmed/15133158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04658504 |
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