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Genetic selection for protein solubility enabled by the folding quality control feature of the twin-arginine translocation pathway
One of the most vexing problems facing structural genomics efforts and the biotechnology enterprise in general is the inability to efficiently produce functional proteins due to poor folding and insolubility. Additionally, protein misfolding and aggregation has been linked to a number of human disea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2249766/ https://ncbi.nlm.nih.gov/pubmed/16452624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051902606 |
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