Adaptor SKAP-55 Binds p21(ras) Activating Exchange Factor RasGRP1 and Negatively Regulates the p21(ras)-ERK Pathway in T-Cells

While the adaptor SKAP-55 mediates LFA-1 adhesion on T-cells, it is not known whether the adaptor regulates other aspects of signaling. SKAP-55 could potentially act as a node to coordinate the modulation of adhesion with downstream signaling. In this regard, the GTPase p21(ras) and the extracellula...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Schneider, Helga, Wang, Hongyan, Raab, Monika, Valk, Elke, Smith, Xin, Lovatt, Matt, Wu, Zhonglin, Maqueira-Iglesias, Braudel, Strebhardt, Klaus, Rudd, Christopher E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249700/
https://ncbi.nlm.nih.gov/pubmed/18320039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001718
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items