Impact of Cytokine Administration on the Generation of Antitumor Reactivity in Patients with Metastatic Melanoma Receiving a Peptide Vaccine

Patients with metastatic melanoma were immunized with an immunodominant peptide derived from the gp100 melanoma-melanocyte differentiation Ag that was modified to increase binding to HLA-A(+)0201. A total of 10 of 11 patients who received the g209–2M peptide alone developed precursors reactive with...

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Autors principals: Rosenberg, Steven A., Yang, James C., Schwartzentruber, Douglas J., Hwu, Patrick, Marincola, Francesco M., Topalian, Suzanne L., Restifo, Nicholas P., Sznol, Mario, Schwarz, Susan L., Spiess, Paul J., Wunderlich, John R., Seipp, Claudia A., Einhorn, Jan H., Rogers-Freezer, Linda, White, Donald E.
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249693/
https://ncbi.nlm.nih.gov/pubmed/10415076
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