Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

The cloning of the genes encoding cancer antigens has opened new possibilities for the treatment of patients with cancer. In this study, immunodominant peptides from the gp100 melanoma-associated antigen were identified, and a synthetic peptide, designed to increase binding to HLA-A2 molecules, was...

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Bibliographic Details
Main Authors: Rosenberg, Steven A., Yang, James C., Schwartzentruber, Douglas J., Hwu, Patrick, Marincola, Francesco M., Topalian, Suzanne L., Restifo, Nicholas P., Dudley, Mark E., Schwarz, Susan L., Spiess, Paul J., Wunderlich, John R., Parkhurst, Maria R., Kawakami, Yutaka, Seipp, Claudia A., Einhorn, Jan H., White, Donald E.
Format: Artigo
Language:Inglês
Published: 1998
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064864/
https://ncbi.nlm.nih.gov/pubmed/9500606
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