Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

The cloning of the genes encoding cancer antigens has opened new possibilities for the treatment of patients with cancer. In this study, immunodominant peptides from the gp100 melanoma-associated antigen were identified, and a synthetic peptide, designed to increase binding to HLA-A2 molecules, was...

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Main Authors: Rosenberg, Steven A., Yang, James C., Schwartzentruber, Douglas J., Hwu, Patrick, Marincola, Francesco M., Topalian, Suzanne L., Restifo, Nicholas P., Dudley, Mark E., Schwarz, Susan L., Spiess, Paul J., Wunderlich, John R., Parkhurst, Maria R., Kawakami, Yutaka, Seipp, Claudia A., Einhorn, Jan H., White, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: 1998
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064864/
https://ncbi.nlm.nih.gov/pubmed/9500606
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