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Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways

The integrin-linked kinase (ILK) is an ankyrin repeat containing serine-threonine protein kinase that can interact directly with the cytoplasmic domains of the β1 and β3 integrin subunits and whose kinase activity is modulated by cell–extracellular matrix interactions. Overexpression of constitutive...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Novak, Anton, Hsu, Shu-Chi, Leung-Hagesteijn, Chungyee, Radeva, Galina, Papkoff, Jackie, Montesano, Roberto, Roskelley, Calvin, Grosschedl, Rudolf, Dedhar, Shoukat
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4374
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