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Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity
Electrostatic interactions are important for molecular recognition processes including Ca(2+)-binding and cell adhesion. To understand these processes, we have successfully introduced a novel Ca(2+)-binding site into the non-Ca(2+)-dependent cell adhesion protein CD2 using our criteria that are spec...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248323/ https://ncbi.nlm.nih.gov/pubmed/18287277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073328208 |
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