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Enhancement of coenzyme binding by a single point mutation at the coenzyme binding domain of E. coli lactaldehyde dehydrogenase

Phenylacetaldehyde dehydrogenase (PAD) and lactaldehyde dehydrogenase (ALD) share some structural and kinetic properties. One difference is that PAD can use NAD(+) and NADP(+), whereas ALD only uses NAD(+). An acidic residue has been involved in the exclusion of NADP(+) from the active site in pyrid...

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Detalhes bibliográficos
Autor principal: Rodríguez-Zavala, José Salud
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248313/
https://ncbi.nlm.nih.gov/pubmed/18218709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073277108
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