Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer

BACKGROUND: Cervical carcinogenesis is a multistep process initiated by "high risk" human papillomaviruses (HR-HPV), most commonly HPV16. The infection per se is, however, not sufficient to induce malignant conversion. Transforming Growth Factor β (TGF-β) inhibits epithelial proliferation...

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Hlavní autoři: Diaz-Chavez, Jose, Hernandez-Pando, Rogelio, Lambert, Paul F, Gariglio, Patricio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248208/
https://ncbi.nlm.nih.gov/pubmed/18184435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-3
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